223rd 2YC3 Conference – San Diego Miramar College

223rd 2YC3 Conference
“Celebrate Partnerships and Innovation”

DATE: August 23-24, 2019

WHERE: San Diego Miramar College

San Diego Miramar College is excited to host the 223rd2YC3Conference (https://2yc3miramar2019.org/) in August 2019. Do you have a unique way that you partner with your students, other faculty, universities, businesses, surrounding community, etc.,to achieve student success? Are you using innovative approaches inside and/or outside of the classroom? We want you to come and share about what you are doing! Our hope is that these two days will be a celebration of the good work that is happening across a variety of two-year schools and highlight the amazing work happening in Chemistry Education. Through these connections, we also anticipate new partnerships being formed and innovative techniques being adopted into classrooms. Come celebrate, innovate, and collaborate! Please contact Gary Smith (glsmith@sdccd.edu) if you would like more information.




DATE: Tuesday, July 9th, 2019

TIME: 9:30 AM

WHERE: Bristol Farms Cafe, Costa Verde Shopping Center
Genesee Avenue and Nobel Drive, University City



Fifty-, Sixty- and Seventy-Year Member Recognition Luncheon

We are celebrating the 50-, 60-, and 70- year members of the San Diego Section of the American Chemical Society with a lunch at Tom Ham’s Lighthouse restaurant!

DATE: July 11th, 2019

11:00 AM Social gathering
12:00 PM Lunch – sumptuous buffet of meat and meatless dishes
12:45 PM Introduction of 50-, 60-, 70-year members

WHERE: Tom Ham’s Lighthouse Restaurant, 2150 Harbor Island Drive, San Diego

RSVP: https://2019sdacsluncheon.eventbrite.com


Organized by Dr. Ben Pratt, Dr. Mark Tichenor, Dr. David Wallace – San Diego Section of the American Chemical Society Dr. Emmanuel Theodorakis – UCSD Department of Chemistry and Biochemistry

DATE: Friday, July 19, 2019

WHERE: Hojel Hall, Institute of the Americas, UC San Diego


8:30 AM Registration and Continental Breakfast 
9:00 AM Opening Remarks: Emmanuel Theodorakis
9:05 AM Dr. Carlo Ballatore, University of California San Diego “Microtubule Stabilizing Small Molecules as Candidate Treatments for Alzheimer’s Disease and Related Tauopathies”
9:50 AM Dr. Punit Seth, Ionis Pharmaceuticals “Targeted Delivery of Nucleic Acid Therapeutics”
10:35 AM Coffee Break
10:50 AM Dr. Scott Rychnovsy, University of California Irvine “Synthetic Approaches to Alkaloids and Terpenes”
11:35 AM Dr. Matt Marx, Mirati Therapeutics “The Discovery of MRTX1257, a Selective, Irreversible Inhibitor of KRAS G12C with Oral Antitumor Activity”
12:20 PM Lunch
1:20 PM Dr. Jeff Gustafson, San Diego State University “New Selectivity Filters to Obtain Selective Inhibitors of RET and Osimertinib Resistant EGFR Mutants”
2:05 PM Dr. Valentina Molteni, The Genomics Institute of the Novartis Research Foundation “Non-steroidal FXR Agonists – Tropifexor and Nidufexor for Chronic Liver Disease”
2:50 PM Symposium Conclusion

To register please visit: http://chemistry.ucsd.edu/go/medchem follow the link to the registration page.
Register online by Friday, July 12, and food will be provided.

Family Picnic 2019 – Free Food & Fun for Families, Friends & Fido!

DATE: Sunday, June 30, 2019

TIME: 11:30 AM – 4:00 PM (food served from approx. noon to 3 PM)

WHERE: San Dieguito County Park, Solana Beach, at Lomas Santa Fe Drive and El Camino Real

DIRECTIONS: Lomas Santa Fe exit off of I-5, one mile east to Highland Drive park entrance. Left onto Highland, immediate right into the park. Pay parking fee ($3.00/car, free for seniors). At booth, proceed to Area #3 Parking. Note: the San Diego County Fair will cause heavy traffic on I-5 near the Lomas Santa Fe exit. Please allow extra driving time!

WHO: Youngsters, seniors, in-betweensters, guys, gals, chemists, recovering chemists, guests and other friends of the ACS!

WHAT: BBQ, cold drinks, games and prizes for children of all ages. Please bring a homemade dessert to enter the Best Dessert Contest. Prizes will be awarded! If you bring a cold dessert, bring a cooler. Guests with special dietary needs should provide for them.

RSVP: As soon as possible but no later than Thursday, June 27th, by registering at https://sdacs2019picnic.eventbrite.com/.

Please tell us how many adults and how many children (with their ages) will be in your party, as well as total number of vegetarians.

Volunteers needed for morning setup!
Please contact James Caldwell to sign up:
tel. 815-262-9697 | email: jcaldwell@sandiegoacs.org

The Southern California Pharmaceutical Discussion Group (SCPDG) of AAPS: A Joint Meeting with the San Diego Section of the ACS

Why Bother? Downstream Development and Market Considerations that Impact Drug Discovery




Vince Wacher, PhD, Synthetic Biologics

Date: Thursday, May 9, 2019

6:00 – 6:30 PM    Check-In
6:30 – 7:15 PM     Dinner
7:15 – 8:15 PM      Presentation
8:15 – 8:30 PM     Discussion

Knobbe Martens, Intellectual Property Law; Da Vinci Conference Room
12790 El Camino Real, El Camino Real, San Diego 92130

RSVP here by Monday, May 6, 2019



Date: Sunday, April 28, 2019

Time: 10 am – 5pm

Place: Balboa Park, San Diego, CA


Please contact James Caldwell, jcaldwell@sandiegoacs.org, to volunteer on Sunday, April 28.

[CANCELLED] Wine Tasting/Chocolate Pairing, Cheese & Fruit Plates, Winery Tour and Social Event at the Bernardo Winery!


The ACS–San Diego Section invites you to join us for an informal evening of socializing, networking and learning!

Date: Thursday, May 23, 2019

6:00 PM – 9:00 PM

Bernardo Winery
13330 Paseo Del Verano Norte San Diego, CA 92128
Tel: (858) 487-1866

COST: $20.00 online, $30.00 at the door

Must RSVP by Monday, May 20th. Must be 21 or older to attend.

* Take a guided, 25-minute walking tour of Southern California’s oldest operating winery.
* Learn about the winemaking process, winery history (1889) and proper tasting techniques. * Enjoy wine tasting paired with chocolate; California cheeses, fruit, rustic bread, etc.
* 2 free drink tickets provided to each guest in addition to the wine tasting.
* Plenty of free, on-site parking!


Date: Tuesday, April 16, 2019

9:30 AM

Bristol Farms Café – Costa Verde Shopping Center
Genesee Avenue and Nobel Drive, University City


Date: Monday, May 20, 2019

6:00 PM Social Hour, Light Supper
7:00 PM Lecture

San Diego State University
Department of Chemistry and Biochemistry GMCS 333
5500 Campanile Drive, San Diego, CA 92182

By Friday, May 17, 2019

From Interstate 8
Take College Ave. Exit and head South. The Chemical Sciences Laboratory (CSL) Building is right next to the exit ramp on College Ave. Stay in the left lane and turn left at the first red light. Drive into Parking Structure 1 and park in any Faculty/Staff slot on Level 1 (no parking permit needed). Take the garage elevator to Floor 6 and walk across the pedestrian bridge over College Avenue. Turn right on Aztec Circle Drive and walk to the GMCS Building (the next building on the right). Lecture Hall GMCS 333 is right behind the first entrance door.

Currently Professor in the CU Department of Chemistry, Dr. Walba also holds an appointment in the CU Department of Chemical and Biological Engineering and serves as the Associate Director of the Soft Materials Research Center.
After receiving a B. S. degree in Chemistry from the University of California at Berkeley (1971), he studied at the California Institute of Technology under the direction of Robert E. Ireland, receiving his Ph.D. on the total synthesis of natural products in 1975. After two years of postdoctoral research on host-guest chemistry with Donald J. Cram at UCLA, Walba started his academic career as Assistant Professor of Chemistry at CU Boulder in 1977, where he has worked since.

Professor Walba’s teaching and research programs emphasize organic chemistry and, in particular, stereochemistry. For his work in teaching and research, he has been made a Fellow of the American Association for the Advancement of Science (1999), a Camille and Henry Dreyfus Teacher Scholar (1984-1986), and a Fellow of the A.P. Sloan Foundation (1982-1984). In addition, Dr. Walba was a co-founder and Vice President for Chemical Research (1984-1994), and member of the Board of Directors (1994-2001) of Displaytech, Inc.

Liquid crystals (LCs) are organic materials exhibiting spontaneous symmetry-breaking in the liquid phase, producing structurally (and optically) anisotropic fluids. Since the discovery of LCs in the late 1880s, chirality has played a key role in the field. Not surprisingly, throughout most of the long history of the study of LCs, the formation of chiral LC phases required enantiomerically enriched chiral molecules – either the LC molecules themselves, or through the addition of chiral dopants.

However, beginning in 1997 the discovery of chiral LC phases formed by achiral or racemic molecules led to the characterization of several variations of spontaneous achiral symmetry-breaking in fluids. These represent fluid analogs of the achiral symmetry breaking occurring upon crystallization of sodium ammonium racemate (racemic tartaric acid) discovered by Pasteur 171 years ago.

LCs showing achiral symmetry breaking are most often (perhaps always) of the “bent-core” variety – the classic example being formation of chiral smectic (layered) phases from a class of resorcinol diesters possessing two “mesogenic” wings. In that system, four diastereomeric phases are formed, two d,l pairs, and two “meso” LC phases. Since the smectic layering is “long-range,” these materials can be considered crystalline in one dimension, though they show fluid rheology.

Then, in 2009, two variants of “dark conglomerates” were described. In these phases, the smectic layering is only short-range, with fluid order giving rise to chiral, optically isotropic fluids (dark between polarizer and analyzer) with optical rotatory power for visible light on the order of 0.1°/μm. Finally, in 2013 bent-core materials possessing fluid order in three dimensions were proven to exist. In these phases, known as “twist-bend nematics,” packing in the fluid phase favors a spontaneous twist, affording an optically anisotropic conglomerate lacking any layering.

These liquid manifestations of Pasteur’s crystal conglomerates will be described.