The Southern California Pharmaceutical Discussion Group (SCPDG) of AAPS: A Joint Meeting with the San Diego Section of the ACS

THE SOUTHERN CALIFORNIA PHARMACEUTICAL DISCUSSION GROUP (SCPDG) OF AAPS
Why Bother? Downstream Development and Market Considerations that Impact Drug Discovery

 

 

 


Speaker:
Vince Wacher, PhD, Synthetic Biologics

Date: Thursday, May 9, 2019

Time:
6:00 – 6:30 PM    Check-In
6:30 – 7:15 PM     Dinner
7:15 – 8:15 PM      Presentation
8:15 – 8:30 PM     Discussion

Place:
Knobbe Martens, Intellectual Property Law; Da Vinci Conference Room
12790 El Camino Real, El Camino Real, San Diego 92130
Map

RSVP:
RSVP here by Monday, May 6, 2019

 

EARTH DAY – EARTHFAIR 2019

Date: Sunday, April 28, 2019

Time: 10 am – 5pm

Place: Balboa Park, San Diego, CA
Map

ABOUT:
http://www.earthdayweb.org/

VOLUNTEERS NEEDED
Please contact James Caldwell, jcaldwell@sandiegoacs.org, to volunteer on Sunday, April 28.

[CANCELLED] Wine Tasting/Chocolate Pairing, Cheese & Fruit Plates, Winery Tour and Social Event at the Bernardo Winery!

THIS EVENT HAS BEEN CANCELLED

The ACS–San Diego Section invites you to join us for an informal evening of socializing, networking and learning!

Date: Thursday, May 23, 2019

Time:
6:00 PM – 9:00 PM

Place:
Bernardo Winery
13330 Paseo Del Verano Norte San Diego, CA 92128
Tel: (858) 487-1866
Map

COST: $20.00 online, $30.00 at the door

RSVP:
https://SDACS2019winetasting.eventbrite.com
Must RSVP by Monday, May 20th. Must be 21 or older to attend.

ABOUT:
* Take a guided, 25-minute walking tour of Southern California’s oldest operating winery.
* Learn about the winemaking process, winery history (1889) and proper tasting techniques. * Enjoy wine tasting paired with chocolate; California cheeses, fruit, rustic bread, etc.
* 2 free drink tickets provided to each guest in addition to the wine tasting.
* Plenty of free, on-site parking!

SENIORS/RETIREES/CONSULTANTS/ETC. BREAKFAST

Date: Tuesday, April 16, 2019

Time:
9:30 AM

Place:
Bristol Farms Café – Costa Verde Shopping Center
Genesee Avenue and Nobel Drive, University City
Map

SPONTANEOUS ACHIRAL SYMMETRY BREAKING IN ORGANIC FLUIDS PROFESSOR DAVID M. WALBA

Date: Monday, May 20, 2019

Time:
6:00 PM Social Hour, Light Supper
7:00 PM Lecture

Place:
San Diego State University
Department of Chemistry and Biochemistry GMCS 333
5500 Campanile Drive, San Diego, CA 92182
Map

RSVP:
By Friday, May 17, 2019
https://davidwalba-sdsu.eventbrite.com

DIRECTIONS:
From Interstate 8
Take College Ave. Exit and head South. The Chemical Sciences Laboratory (CSL) Building is right next to the exit ramp on College Ave. Stay in the left lane and turn left at the first red light. Drive into Parking Structure 1 and park in any Faculty/Staff slot on Level 1 (no parking permit needed). Take the garage elevator to Floor 6 and walk across the pedestrian bridge over College Avenue. Turn right on Aztec Circle Drive and walk to the GMCS Building (the next building on the right). Lecture Hall GMCS 333 is right behind the first entrance door.

ABOUT THE SPEAKER:
Currently Professor in the CU Department of Chemistry, Dr. Walba also holds an appointment in the CU Department of Chemical and Biological Engineering and serves as the Associate Director of the Soft Materials Research Center.
After receiving a B. S. degree in Chemistry from the University of California at Berkeley (1971), he studied at the California Institute of Technology under the direction of Robert E. Ireland, receiving his Ph.D. on the total synthesis of natural products in 1975. After two years of postdoctoral research on host-guest chemistry with Donald J. Cram at UCLA, Walba started his academic career as Assistant Professor of Chemistry at CU Boulder in 1977, where he has worked since.

Professor Walba’s teaching and research programs emphasize organic chemistry and, in particular, stereochemistry. For his work in teaching and research, he has been made a Fellow of the American Association for the Advancement of Science (1999), a Camille and Henry Dreyfus Teacher Scholar (1984-1986), and a Fellow of the A.P. Sloan Foundation (1982-1984). In addition, Dr. Walba was a co-founder and Vice President for Chemical Research (1984-1994), and member of the Board of Directors (1994-2001) of Displaytech, Inc.

ABOUT THE PRESENTATION:
Liquid crystals (LCs) are organic materials exhibiting spontaneous symmetry-breaking in the liquid phase, producing structurally (and optically) anisotropic fluids. Since the discovery of LCs in the late 1880s, chirality has played a key role in the field. Not surprisingly, throughout most of the long history of the study of LCs, the formation of chiral LC phases required enantiomerically enriched chiral molecules – either the LC molecules themselves, or through the addition of chiral dopants.

However, beginning in 1997 the discovery of chiral LC phases formed by achiral or racemic molecules led to the characterization of several variations of spontaneous achiral symmetry-breaking in fluids. These represent fluid analogs of the achiral symmetry breaking occurring upon crystallization of sodium ammonium racemate (racemic tartaric acid) discovered by Pasteur 171 years ago.

LCs showing achiral symmetry breaking are most often (perhaps always) of the “bent-core” variety – the classic example being formation of chiral smectic (layered) phases from a class of resorcinol diesters possessing two “mesogenic” wings. In that system, four diastereomeric phases are formed, two d,l pairs, and two “meso” LC phases. Since the smectic layering is “long-range,” these materials can be considered crystalline in one dimension, though they show fluid rheology.

Then, in 2009, two variants of “dark conglomerates” were described. In these phases, the smectic layering is only short-range, with fluid order giving rise to chiral, optically isotropic fluids (dark between polarizer and analyzer) with optical rotatory power for visible light on the order of 0.1°/μm. Finally, in 2013 bent-core materials possessing fluid order in three dimensions were proven to exist. In these phases, known as “twist-bend nematics,” packing in the fluid phase favors a spontaneous twist, affording an optically anisotropic conglomerate lacking any layering.

These liquid manifestations of Pasteur’s crystal conglomerates will be described.

THE DRUG HUNTER AWARD SEMINAR SERIES INTEGRATING MOLECULAR ENDOCRINOLOGY TO DISCOVER NEXT GENERATION DRUGS FOR BREAST AND PROSTATE CANCER

Speaker: Richard A. Heyman, Ph.D.

Date: Monday, March 11, 2019

Time:
4:00 PM

Place:
Pharmacy School, UC San Diego

 

Introduction to Lilly Life Sciences Studio (L2S2) – Medicinal Chemistry and Automation

Date: Tuesday, March 26, 2019

Time:
6:00 PM – 7:00 PM Networking & Light Dinner
7:00 PM – 7:30 PM Seminar
7:30 PM – 9:00 PM Tour of L2S2 Facility

Place: Lilly Biotechnology Center, 10290 Campus Point Drive, San Diego, CA 92121
Map

RSVP:
https://lillyevent.eventbrite.com
There will be a registration limit of 80

ABOUT THE SPEAKERS:
Todd DeCollo
is a research scientist in the discovery automation research group at Lilly Biotechnology Center in San Diego, performing drug discovery research in the L2S2 facility.

Jimmy Sastra is the vice president of automation at Transcriptic, Inc. Lilly has licensed technology from Transcriptic to enable remotely accessible drug discovery operations at the L2S2 facility.

ABOUT THE PRESENTATION:
The talk will only last about 30 minutes, as the rest of the time will be dedicated to the tour of the facility. The talk will introduce the audience to the L2S2 facility and the type of organic chemical synthesis that takes place in the automated system. The tour will demonstrate the chemical synthesis in action.

The 65th Annual Greater San Diego Science and Engineering Fair

Date: Februrary 12-17, 2019

Place: Balboa Park Activity Center, 2145 Park
Map

Info:
https://www.gsdsef.org/

 

Science Fair Week:

Tuesday, March 12, 2019 – Check-In and Project Set-Up – Balboa Park Activity Center

Wednesday, March 13, 2019 – Judging Day – Balboa Park Activity Center

Thursday, March 14, 2019 – Awards Ceremony – Viejas Arena, San Diego State University

Thursday, March 14, 2019 – Student Science Tours

Friday, March 15, 2019 – Student Science Tours

Thursday, March 14 – Sunday, March 17, 2019 – Public Viewing Days

Sunday, March 17, 2019 – Family Day (Fun Science Activities for the whole family!) presented by the Student Leadership Board – Balboa Park Activity Center

San Diego Festival of Science & Engineering Expo Day at Petco Park

Date: Saturday, March 2, 2019

Place:
Petco Park

Time:
10:00 AM – 5:00 PM

More info: https://www.lovestemsd.org/

Uncovering the Secrets of Ancient and Medieval Artists

Date: Wednesday, Februrary 6, 2019

Time:
4:00 PM

Place:
California State University San Marcos, University Hall 100
Enter the campus on Craven Drive, follow the signs to Lot F to purchase a parking permit, then walk to University Hall 100

RSVP:
Jackie Trischman at trischma@csusm.edu

ABOUT THE PRESENTATION: Chemical detective work in the form of modern chemical methods can be used to examine both ancient and medieval artifacts. Orna will discuss the ways these probes are used in: clarifying the techniques used in making these objects, determining their content, and dating their origins. The variety of methods used in the examination of such materials as ancient textiles, pigments in medieval manuscripts, medieval stained glass, Middle Eastern obsidian and pottery, and 20th century art forgeries will be discussed. Although those methods give great insight into the objects in question, there are limits to such technology; the limitations of those techniques will be presented.